Rehabilitation neuroplasticity emphasizes the potential of the brain to reorganize and create new neural circuits after disease or injury. Training methods like task-specific training, constraint-induced movement therapy, and repetitive practice trigger neuroplastic changes. Physiatrists and occupational therapists plan customized programs to achieve peak motor, cognitive, and functional recovery. Neuroplasticity enhancement promotes better independence, decreased disability, and better quality of life for patients with stroke, TBI, or neurodegenerative conditions.